For studies on successful aging, resources of lymphoblastoid cell lines(LCL) and LCL derived DNA samples from octogenarians, nonagenarians and centenarians are available from the NIA Aging Cell Repository. For each of these collections, the cell lines/DNA were prepared from blood samples that were donated by men and women who have reached great age and whose current health is good, though not necessarily completely healthy. Most donors were interviewed to collect critical information about their age, medical history, family medical history, and demographics. The samples include:

• Aged Sib Pairs Collection
  
  The individuals listed in this collection were sought from elder care facilities in the US specifically because they are members of families with at least one other sibling who lived to be over the age of 80.
  
  
• Longevity Research Collection
  
  Volunteers who had reached the age of 80 or older were sought from elder care facilties in the US for this research project. Subjects were interviewed with respect to medical history and lifestyle before sampling. The data are self-reported although every effort was made to verify their age. The detailed information about Longevity Research collection participants is summarized in a downloadable Excel File.
  
  
• Sardinian Population of Great Age
  
  These individuals are from San Pietro, an island off the southwest coast of Sardinia where many residents attain a great age.
  
  
• Georgia Centenarian Collection
  
  The Georgia Centenarian Collection includes DNA and lymphoblastoid cell lines from individuals from 98 to 108 years of age who were enrolled in the Georgia Centenarian Study. Young control individuals range in age from 20 to 59. The EBV-transformed cell lines were prepared from whole blood samples. DNA samples (10 micrograms) can be ordered individually or in panels. Samples are supplied with gender, race and age at time of collection. Investigators can request additional data associated with the study from the Georgia Centenarian Study website.

  Available information about the participants is summarized in a downloadable Excel file with worksheets organized by race and age.

  DNA panels available:

  • Caucasian Panel of Great Age (N=100)
  • Caucasian Panel of Young Controls (N=100)
  • African American Panel of Great Age (N=32)
  • African American Panel of Young Controls (N=78)

Custom-made 96-well plates of DNA

Investigators can place custom orders for creation of 96-well plates of the DNA samples of their choosing. Contact NIA Repository principal investigator Margaret Keller, PhD to request information about custom-plate orders.